Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1

Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1

Peroxisome proliferator-activated receptors (PPARs) control the transcription of genes involved in lipid metabolism. Activation of PPARδ may have antiatherogenic effects through the increase of plasma HDL, theoretically promoting reverse cholesterol transport from peripheral tissues toward the liver...

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Bibliographic Details
Main Authors: Jelske N. van der Veen, Janine K. Kruit, Rick Havinga, Julius F.W. Baller, Giovanna Chimini, Sophie Lestavel, Bart Staels, Pieter H.E. Groot, Albert K. Groen, Folkert Kuipers
Format: Article
Language:English
Published: Elsevier 2005-03-01
Series:Journal of Lipid Research
Subjects:
Niemann-Pick C1-like 1
peroxisome proliferator-activated receptor δ
nuclear receptors
high density lipoprotein-cholesterol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340372

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http://www.sciencedirect.com/science/article/pii/S0022227520340372

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