Therapeutic Modulation of the Complement Cascade in Stroke

Therapeutic Modulation of the Complement Cascade in Stroke

Stroke is a leading cause of death and disability worldwide and an increasing number of ischemic stroke patients are undergoing pharmacological and mechanical reperfusion. Both human and experimental models of reperfused ischemic stroke have implicated the complement cascade in secondary tissue inju...

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Bibliographic Details
Main Authors: Alison R. Clarke, Brandon R. Christophe, Anadjeet Khahera, Justin L. Sim, E. Sander Connolly
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
complement
vascular disorders
complement activation
cerebral blood flow
complement cascade
stroke therapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01723/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01723/full

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