Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer

Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer

Circulating tumor DNA (ctDNA) is emerging as a key potential biomarker for post-diagnosis surveillance but it may also play a crucial role in the detection of pre-clinical cancer. Small-cell lung cancer (SCLC) is an excellent candidate for early detection given there are no successful therapeutic op...

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Bibliographic Details
Main Authors: Lynnette Fernandez-Cuesta, Sandra Perdomo, Patrice H. Avogbe, Noemie Leblay, Tiffany M. Delhomme, Valerie Gaborieau, Behnoush Abedi-Ardekani, Estelle Chanudet, Magali Olivier, David Zaridze, Anush Mukeria, Marta Vilensky, Ivana Holcatova, Jerry Polesel, Lorenzo Simonato, Cristina Canova, Pagona Lagiou, Christian Brambilla, Elisabeth Brambilla, Graham Byrnes, Ghislaine Scelo, Florence Le Calvez-Kelm, Matthieu Foll, James D. McKay, Paul Brennan
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:EBioMedicine
Subjects:
ctDNA
cfDNA
Small-cell lung cancer
TP53 mutations
Early detection
Screening
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416302894

Internet

http://www.sciencedirect.com/science/article/pii/S2352396416302894

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