Myxoma Virus-Loaded Mesenchymal Stem Cells in Experimental Oncolytic Therapy of Murine Pulmonary Melanoma

Myxoma Virus-Loaded Mesenchymal Stem Cells in Experimental Oncolytic Therapy of Murine Pulmonary Melanoma

Oncolytic viruses can target neoplasms, triggering oncolytic and immune effects. Their delivery to melanoma lesions remains challenging. Bone-marrow-derived mesenchymal stem cells (MSCs) were shown to be permissive for oncolytic myxoma virus (MYXV), allowing its transfer to melanoma cells, leading t...

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Bibliographic Details
Main Authors: Joanna Jazowiecka-Rakus, Aleksander Sochanik, Aleksandra Rusin, Agata Hadryś, Wojciech Fidyk, Nancy Villa, Masmudur M. Rahman, Ewa Chmielik, Lina S. Franco, Grant McFadden
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
mesenchymal stem cells
myxoma virus
melanoma
oncolytic virotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301078

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http://www.sciencedirect.com/science/article/pii/S2372770520301078

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