Cellular and behavioral effects of lipopolysaccharide treatment are dependent upon neurokinin-1 receptor activation

Cellular and behavioral effects of lipopolysaccharide treatment are dependent upon neurokinin-1 receptor activation

Abstract Background Several psychiatric conditions are affected by neuroinflammation and neuroimmune activation. The transcription factor nuclear factor kappa light-chain-enhancer of activated B cells (NFkB) plays a major role in inflammation and innate immunity. The neurokinin-1 receptor (NK1R) is...

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Bibliographic Details
Main Authors: Hannah D. Fulenwider, Britessia M. Smith, Anna S. Nichenko, Jessica M. Carpenter, Sadie E. Nennig, Kejun Cheng, Kenner C. Rice, Jesse R. Schank
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Neuroinflammation
Subjects:
Neurokinin-1 receptor
Nuclear factor kappa B
Lipopolysaccharide
Inflammation
Cytokines
Anhedonia
Online Access:http://link.springer.com/article/10.1186/s12974-018-1098-4

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http://link.springer.com/article/10.1186/s12974-018-1098-4

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