Free water: A marker of age-related modifications of the cingulum white matter and its association with cognitive decline.

Diffusion MRI is extensively used to investigate changes in white matter microstructure. However, diffusion measures within white matter tissue can be affected by partial volume effects due to cerebrospinal fluid and white matter hyperintensities, especially in the aging brain. In previous aging stu...

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Bibliographic Details
Main Authors: Manon Edde, Guillaume Theaud, François Rheault, Bixente Dilharreguy, Catherine Helmer, Jean-François Dartigues, Hélène Amieva, Michèle Allard, Maxime Descoteaux, Gwénaëlle Catheline
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242696