Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

Transcriptional Activity and Stability of CD39+CD103+CD8+ T Cells in Human High-Grade Endometrial Cancer

Tumor-infiltrating CD8+ T cells (TIL) are of the utmost importance in anti-tumor immunity. CD103 defines tumor-resident memory T cells (T<sub>RM</sub> cells) associated with improved survival and response to immune checkpoint blockade (ICB) across human tumors. Co-expression of CD39 and...

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Bibliographic Details
Main Authors: Hagma H. Workel, Nienke van Rooij, Annechien Plat, Diana C.J. Spierings, Rudolf S. N. Fehrmann, Hans W. Nijman, Marco de Bruyn
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
tissue-resident memory cell
endometrial cancer
CD103
CD39
transcript stability
cytokinesis
Online Access:https://www.mdpi.com/1422-0067/21/11/3770

Internet

https://www.mdpi.com/1422-0067/21/11/3770

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