The Antimicrobial Peptide Human Beta-Defensin 2 Inhibits Biofilm Production of Pseudomonas aeruginosa Without Compromising Metabolic Activity

The Antimicrobial Peptide Human Beta-Defensin 2 Inhibits Biofilm Production of Pseudomonas aeruginosa Without Compromising Metabolic Activity

Biofilm production is a key virulence factor that facilitates bacterial colonization on host surfaces and is regulated by complex pathways, including quorum sensing, that also control pigment production, among others. To limit colonization, epithelial cells, as part of the first line of defense, uti...

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Bibliographic Details
Main Authors: Kevin R. Parducho, Brent Beadell, Tiffany K. Ybarra, Mabel Bush, Erick Escalera, Aldo T. Trejos, Andy Chieng, Marlon Mendez, Chance Anderson, Hyunsook Park, Yixian Wang, Wuyuan Lu, Edith Porter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
airways
antimicrobial peptides
biofilm
cystic fibrosis
epithelial cells
innate immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00805/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00805/full

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