Potassium dependent rescue of a myopathy with core-like structures in mouse
Myopathies decrease muscle functionality. Mutations in ryanodine receptor 1 (RyR1) are often associated with myopathies with microscopic core-like structures in the muscle fiber. In this study, we identify a mouse RyR1 model in which heterozygous animals display clinical and pathological hallmarks o...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/02923 |