The influence of CYP2C8*3 on carbamazepine serum concentration in epileptic pediatric patients

The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment. Genotyping was conducted using polymerase chain reaction-restriction frag...

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Bibliographic Details
Main Authors: Milovanovic DD, Milovanovic JR, Radovanovic M, Radosavljevic I, Obradovic S, Jankovic S, Milovanovic D, Djordjevic N
Format: Article
Language:English
Published: Sciendo 2016-06-01
Series:Balkan Journal of Medical Genetics
Subjects:
Online Access:https://doi.org/10.1515/bjmg-2016-0003