Immunization With a Combination of Four Recombinant Brucella abortus Proteins Omp16, Omp19, Omp28, and L7/L12 Induces T Helper 1 Immune Response Against Virulent B. abortus 544 Infection in BALB/c Mice

Immunization With a Combination of Four Recombinant Brucella abortus Proteins Omp16, Omp19, Omp28, and L7/L12 Induces T Helper 1 Immune Response Against Virulent B. abortus 544 Infection in BALB/c Mice

Protective efficiency of a combination of four recombinant Brucella abortus (B. abortus) proteins, namely outer membrane protein (Omp) 16, Omp19, Omp28, and 50S ribosomal protein L7/L12 was evaluated as a combined subunit vaccine (CSV) against B. abortus infection in RAW 264.7 cell line and murine m...

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Bibliographic Details
Main Authors: Tran Xuan Ngoc Huy, Trang Thi Nguyen, Alisha Wehdnesday Bernardo Reyes, Son Hai Vu, WonGi Min, Hu Jang Lee, John Hwa Lee, Suk Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Veterinary Science
Subjects:
Brucella abortus
combined subunit vaccine
T helper 1 T cell
humoral immunity
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2020.577026/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2020.577026/full

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