Proximity to dementia onset and multi-modal neuroimaging changes: The prevent-dementia study

Background: First-degree relatives of people with dementia (FH+) are at increased risk of developing Alzheimer's disease (AD). Here, we investigate “estimated years to onset of dementia” (EYO) as a surrogate marker of preclinical disease progression and assess its associations with multi-modal...

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Bibliographic Details
Main Authors: Elijah Mak, Maria-Eleni Dounavi, Audrey Low, Stephen F. Carter, Elizabeth McKiernan, Guy B Williams, P Simon Jones, Isabelle Carriere, Graciela Terrera Muniz, Karen Ritchie, Craig Ritchie, Li Su, John T O'Brien
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:NeuroImage
Subjects:
MRI
DTI
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921000264