Combined treatment with N‐acetylcysteine and gefitinib overcomes drug resistance to gefitinib in NSCLC cell line

Abstract We aimed to explore the molecular substrate underlying EGFR‐TKI resistance and investigate the effects of N‐acetylcysteine (NAC) on reversing EGFR‐TKI resistance. In the current research, the effects of NAC in combination with gefitinib on reversing gefitinib resistance were examined using...

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Bibliographic Details
Main Authors: Jun Li, Xiao‐Hui Wang, Jing Hu, Meng Shi, Lu Zhang, Hong Chen
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Cancer Medicine
Subjects:
Src
Online Access:https://doi.org/10.1002/cam4.2610