CCL22 induces pro-inflammatory changes in fibroblast-like synoviocytes

Summary: Synovitis is common in patients with osteoarthritis (OA) and is associated with pain and disease progression. We have previously demonstrated that the chemokine C-C motif chemokine 22 (CCL22) induces chondrocyte apoptosis in vitro; however, the effects of CCL22 on the synovium remain unknow...

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Bibliographic Details
Main Authors: Guomin Ren, Nedaa Al-Jezani, Pamela Railton, James N. Powell, Roman J. Krawetz
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311408