Loss of HCN2 in Dorsal Hippocampus of Young Adult Mice Induces Specific Apoptosis of the CA1 Pyramidal Neuron Layer

Loss of HCN2 in Dorsal Hippocampus of Young Adult Mice Induces Specific Apoptosis of the CA1 Pyramidal Neuron Layer

Neurons inevitably rely on a proper repertoire and distribution of membrane-bound ion-conducting channels. Among these proteins, the family of hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels possesses unique properties giving rise to the corresponding I<sub>h</sub>...

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Bibliographic Details
Main Authors: Matthias Deutsch, Carina Stegmayr, Sabine Balfanz, Arnd Baumann
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Adeno-associated virus (AAV)
hyperpolarization-activated and cyclic nucleotide-gated ion channel (HCN-channel)
immunocytochemistry
knock-down
pacemaker channel
patch-clamp
Online Access:https://www.mdpi.com/1422-0067/22/13/6699

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https://www.mdpi.com/1422-0067/22/13/6699

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