AAV-Mediated CRISPRi and RNAi Based Gene Silencing in Mouse Hippocampal Neurons

Uncovering the physiological role of individual proteins that are part of the intricate process of cellular signaling is often a complex and challenging task. A straightforward strategy of studying a protein’s function is by manipulating the expression rate of its gene. In recent years, the Clustere...

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Bibliographic Details
Main Authors: Matthias Deutsch, Anne Günther, Rodrigo Lerchundi, Christine R. Rose, Sabine Balfanz, Arnd Baumann
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/324