MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression

Summary: The Mediator complex relays regulatory signals from gene-specific transcription factors to the basal transcriptional machinery. However, the role of individual Mediator subunits in different tissues remains unclear. Here, we demonstrate that MED19 is essential for adipogenesis and maintenan...

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Bibliographic Details
Main Authors: John M. Dean, Anyuan He, Min Tan, Jun Wang, Dongliang Lu, Babak Razani, Irfan J. Lodhi
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720312171