Labour-efficient in vitro lymphocyte population tracking and fate prediction using automation and manual review.

Interest in cell heterogeneity and differentiation has recently led to increased use of time-lapse microscopy. Previous studies have shown that cell fate may be determined well in advance of the event. We used a mixture of automation and manual review of time-lapse live cell imaging to track the pos...

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Bibliographic Details
Main Authors: Rajib Chakravorty, David Rawlinson, Alan Zhang, John Markham, Mark R Dowling, Cameron Wellard, Jie H S Zhou, Philip D Hodgkin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3880260?pdf=render