Protocol for the Maintenance of Quiescent Murine Hematopoietic Stem Cells

Summary: Mammalian hematopoietic stem cells (HSCs) maintain life-long hematopoiesis in the bone marrow. HSCs remain quiescent in vivo, unlike more differentiated progenitors, and enter the cell cycle rapidly after bone marrow injury or in vitro culture. We have recently demonstrated the ability to m...

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Bibliographic Details
Main Authors: Hiroshi Kobayashi, Keiyo Takubo
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:STAR Protocols
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166720300654