Chiral Cyclobutane-Containing Cell-Penetrating Peptides as Selective Vectors for Anti-<i>Leishmania</i> Drug Delivery Systems

Chiral Cyclobutane-Containing Cell-Penetrating Peptides as Selective Vectors for Anti-<i>Leishmania</i> Drug Delivery Systems

Two series of new hybrid γ/γ-peptides, γ-CC and γ-CT, formed by (1<i>S</i>,2<i>R</i>)-3-amino-2,2,dimethylcyclobutane-1-carboxylic acid joined in alternation to a <i>N</i><sup>α</sup>-functionalized <i>cis</i>- or <i>trans</i>-γ...

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Bibliographic Details
Main Authors: Ona Illa, José-Antonio Olivares, Nerea Gaztelumendi, Laura Martínez-Castro, Jimena Ospina, María-Ángeles Abengozar, Giuseppe Sciortino, Jean-Didier Maréchal, Carme Nogués, Míriam Royo, Luis Rivas, Rosa M. Ortuño
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
unnatural γ-amino acids
foldamers
selective cell-penetrating peptides
anti-<i>Leishmania</i> drug delivery vectors
Online Access:https://www.mdpi.com/1422-0067/21/20/7502

Internet

https://www.mdpi.com/1422-0067/21/20/7502

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