A Pimarane Diterpene and Cytotoxic Angucyclines from a Marine-Derived Micromonospora sp. in Vietnam’s East Sea

A Pimarane Diterpene and Cytotoxic Angucyclines from a Marine-Derived Micromonospora sp. in Vietnam’s East Sea

A screening of our actinomycete fraction library against the NCI-60 SKOV3 human tumor cell line led to the isolation of isopimara-2-one-3-ol-8,15-diene (1), lagumycin B (2), dehydrorabelomycin (3), phenanthroviridone (4), and WS-5995 A (5). These secondary metabolites were produced by a Micromonospo...

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Bibliographic Details
Main Authors: Michael W. Mullowney, Eoghainín Ó hAinmhire, Urszula Tanouye, Joanna E. Burdette, Van Cuong Pham, Brian T. Murphy
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Marine Drugs
Subjects:
actinomycete
marine
Micromonospora
ovarian cancer
Vietnam
diterpene
Online Access:http://www.mdpi.com/1660-3397/13/9/5815

Internet

http://www.mdpi.com/1660-3397/13/9/5815

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