Alterations in Lipoxygenase and Cyclooxygenase-2 Catalytic Activity and mRNA Expression in Prostate Carcinoma

Alterations in Lipoxygenase and Cyclooxygenase-2 Catalytic Activity and mRNA Expression in Prostate Carcinoma

Recent studies in prostate tissues and especially cell lines have suggested roles for arachidonic acid (AA) metabolizing enzymes in prostate adenocarcinoma (Pca) development or progression. The goal of this study was to more fully characterize lipoxygenase (LOX) and cyclooxygenase-2 (COX-2) gene ex...

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Bibliographic Details
Main Authors: Scott B. Shappell, Suzanne Manning, William E. Boeglin, You-Fei Guan, Richard L. Roberts, Linda Davis, Sandra J. Olson, Gregory S. Jack, Christopher S. Coffey, Thomas M. Wheeler, Matthew D. Breyer, Alan R. Brash
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
arachidonic acid
eicosanoids
HETEs
15-lipoxygenase-2
cyclooxygenase
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800324

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http://www.sciencedirect.com/science/article/pii/S1476558601800324

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