Discovery of Novel Small Molecules that Block Myofibroblast Formation: Implications for Capsular Contracture Treatment
Background:. Capsular contracture is a devastating complication that occurs in patients undergoing implant-based breast reconstruction. Ionizing radiation drives and exacerbates capsular contracture in part by activating cytokines, including transforming growth factor-beta (TGF-β). TGF-β promotes my...
Main Authors: | Rachel H. Park, BA, Stephen J. Pollock, BSc, Richard P. Phipps, PhD, Howard N. Langstein, MD, Collynn F. Woeller, PhD |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2019-09-01
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Series: | Plastic and Reconstructive Surgery, Global Open |
Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002430 |
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