Designing experiments to discriminate families of logic models

Designing experiments to discriminate families of logic models

Logic models of signaling pathways are a promising way of building effective in silico functional models of a cell, in particular of signaling pathways. The automated learning of Boolean logic models describing signaling pathways can be achieved by training to phosphoproteomics data, which is partic...

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Bibliographic Details
Main Authors: Santiago eVidela, Irina eKonokotina, Leonidas eAlexopoulos, Julio eSaez-Rodriguez, Torsten eSchaub, Anne eSiegel, Carito eGuziolowski
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
experimental design
phosphoproteomics
signaling networks
answer set programming
Boolean logic models
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00131/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00131/full

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