Dengue viruses are enhanced by distinct populations of serotype cross-reactive antibodies in human immune sera.

Dengue viruses (DENV) are mosquito-borne flaviviruses of global importance. DENV exist as four serotypes, DENV1-DENV4. Following a primary infection, individuals produce DENV-specific antibodies that bind only to the serotype of infection and other antibodies that cross-react with two or more seroty...

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Bibliographic Details
Main Authors: Ruklanthi de Alwis, Katherine L Williams, Michael A Schmid, Chih-Yun Lai, Bhumi Patel, Scott A Smith, James E Crowe, Wei-Kung Wang, Eva Harris, Aravinda M de Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4183589?pdf=render