Prion protein expression and processing in human mononuclear cells: the impact of the codon 129 prion gene polymorphism.
BACKGROUND:So far, all clinical cases of new variant Creutzfeldt-Jakob disease (vCJD), thought to result from the Bovine Spongiform Encephalopathy (BSE) prion agent, have shown Methionine-Methionine (M/M) homozygosity at the M129V polymorphism of the PRNP gene. Although established, this relationshi...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-06-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2686158?pdf=render |