Multiple cancer pathways regulate telomere protection

Multiple cancer pathways regulate telomere protection

Abstract Telomeres are considered as universal anti‐cancer targets, as telomere maintenance is essential to sustain indefinite cancer growth. Mutations in telomerase, the enzyme that maintains telomeres, are among the most frequently found in cancer. In addition, mutations in components of the telom...

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Bibliographic Details
Main Authors: Leire Bejarano, Giuseppe Bosso, Jessica Louzame, Rosa Serrano, Elena Gómez‐Casero, Jorge Martínez‐Torrecuadrada, Sonia Martínez, Carmen Blanco‐Aparicio, Joaquín Pastor, Maria A Blasco
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:EMBO Molecular Medicine
Subjects:
drug resistance
ERK kinase
glioblastoma
telomeres
TRF1 inhibitors
Online Access:https://doi.org/10.15252/emmm.201910292

Internet

https://doi.org/10.15252/emmm.201910292

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