Multiple cancer pathways regulate telomere protection
Abstract Telomeres are considered as universal anti‐cancer targets, as telomere maintenance is essential to sustain indefinite cancer growth. Mutations in telomerase, the enzyme that maintains telomeres, are among the most frequently found in cancer. In addition, mutations in components of the telom...
Main Authors: | Leire Bejarano, Giuseppe Bosso, Jessica Louzame, Rosa Serrano, Elena Gómez‐Casero, Jorge Martínez‐Torrecuadrada, Sonia Martínez, Carmen Blanco‐Aparicio, Joaquín Pastor, Maria A Blasco |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-07-01
|
Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.15252/emmm.201910292 |
Similar Items
-
Clinical Significance of Telomere Length and Associated Proteins in Oral Cancer
by: Rachana N. Sainger, et al.
Published: (2007-01-01) -
Duplex Telomere-Binding Proteins in Fungi With Canonical Telomere Repeats: New Lessons in the Rapid Evolution of Telomere Proteins
by: Neal F. Lue, et al.
Published: (2021-02-01) -
The Outer Limits: Telomere Maintenance by TRF2 and G-Quadruplex DNA Structures
by: Pedroso, Ilene Marie
Published: (2008) -
The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage Response
by: Siti A. M. Imran, et al.
Published: (2021-09-01) -
Telomere Length Diversity in Cattle Breeds
by: Alessio Valentini, et al.
Published: (2010-08-01)