Screening for mutations in selected miRNA genes in hypogonadotropic hypogonadism patients

In approximately half of congenital hypogonadotropic hypogonadism (cHH) patients, the genetic cause remains unidentified. Since the lack of certain mi RNAs in animal models has led to cHH, we sequenced human miRNAs predicted to regulate cHH-related genes (MIR7-3, MIR141, MIR429 and MIR200A-C) in 24...

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Bibliographic Details
Main Authors: Anna-Pauliina Iivonen, Johanna Känsäkoski, Kirsi Vaaralahti, Taneli Raivio
Format: Article
Language:English
Published: Bioscientifica 2019-04-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/5/EC-19-0080.xml