RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus

RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus

Human rhinovirus (HRV) causes upper respiratory infections and asthma exacerbations. We screened multiple orthologous RNAi reagents and identified host proteins that modulate HRV replication. Here, we show that RNASEK, a transmembrane protein, was needed for the replication of HRV, influenza A virus...

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Bibliographic Details
Main Authors: Jill M. Perreira, Aaron M. Aker, George Savidis, Christopher R. Chin, William M. McDougall, Jocelyn M. Portmann, Paul Meraner, Miles C. Smith, Motiur Rahman, Richard E. Baker, Annick Gauthier, Michael Franti, Abraham L. Brass
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715007263

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http://www.sciencedirect.com/science/article/pii/S2211124715007263

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