Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients

Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients

Abstract The determinants of clinical responses after autologous hematopoietic stem cell transplantation (aHSCT) in systemic sclerosis (SSc) are still unraveled. We analyzed long-term immune reconstitution (IR) and T cell receptor (TCR) repertoire diversity in 10 SSc patients, with at least 6 years...

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Bibliographic Details
Main Authors: Dominique Farge, Lucas C. M. Arruda, Fanny Brigant, Emmanuel Clave, Corinne Douay, Zora Marjanovic, Christophe Deligny, Guitta Maki, Eliane Gluckman, Antoine Toubert, Helene Moins-Teisserenc
Format: Article
Language:English
Published: BMC 2017-01-01
Series:Journal of Hematology & Oncology
Subjects:
Systemic sclerosis
T cell repertoire
Immune reconstitution
Hematopoietic stem cell transplantation
Online Access:http://link.springer.com/article/10.1186/s13045-016-0388-5

Internet

http://link.springer.com/article/10.1186/s13045-016-0388-5

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