Escape from the phagosome: the explanation for MHC-I processing of mycobacterial antigens?

Mycobacterium tuberculosis (Mtb) is thought to live in an altered phagosomal environment. In this setting, the mechanisms by which mycobacterial antigens access the major histocompatibility class I (MHC-I) processing machinery remain incompletely understood. There is evidence that Mtb antigens can b...

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Bibliographic Details
Main Authors: Melanie eHarriff, Georgiana ePurdy, David M Lewinsohn
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00040/full