Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells

Innate T cells such as iNKT, MAIT and γδ T cells all develop in the thymus, but their differentiation paths are still unclear. Here, the authors show, using single-cell RNA sequencing, that all three cell types develop via shared and branched differentiation paths that are corroborated by additional...

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Bibliographic Details
Main Authors: Minji Lee, Eunmin Lee, Seong Kyu Han, Yoon Ha Choi, Dong-il Kwon, Hyobeen Choi, Kwanghwan Lee, Eun Seo Park, Min-Seok Rha, Dong Jin Joo, Eui-Cheol Shin, Sanguk Kim, Jong Kyoung Kim, You Jeong Lee
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18155-8