Dynamics of mcr-1 prevalence and mcr-1-positive Escherichia coli after the cessation of colistin use as a feed additive for animals in China: a prospective cross-sectional and whole genome sequencing-based molecular epidemiological study

Summary: Background: The global dissemination of colistin resistance encoded by mcr-1 has been attributed to extensive use of colistin in livestock, threatening colistin efficacy in medicine. The emergence of mcr-1 in common pathogens, such as Escherichia coli, is of particular concern. China banne...

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Main Authors: Cong Shen, BS, Lan-Lan Zhong, MS, Yongqiang Yang, PhD, Yohei Doi, ProfMD, David L Paterson, ProfMD, Nicole Stoesser, MD, Furong Ma, BS, Mohamed Abd El-Gawad El-Sayed Ahmed, PhD, Siyuan Feng, PhD, Songyin Huang, ProfMD, Hong-Yu Li, ProfMD, Xi Huang, ProfPhD, Xin Wen, BS, Zihan Zhao, MS, Minmin Lin, BS, Guanping Chen, BS, Wanfei Liang, BS, MS, Yingjian Liang, Yong Xia, ProfMD, Min Dai, ProfMD, Ding-Qiang Chen, ProfMD, Liyan Zhang, ProfMD, Kang Liao, ProfMD, Guo-Bao Tian, ProfPhD
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:The Lancet Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666524720300057