Biomimetic properties and estimated in vivo distribution of chloroquine and hydroxy-chloroquine enantiomers

Chloroquine and hydroxy-chloroquine already established as anti-malarial and lupus drugs have recently gained renewed attention in the fight against the Covid-19 pandemic. Bio-mimetic HPLC methods have been used to measure the protein and phospholipid binding of the racemic mixtures of the drugs. T...

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Bibliographic Details
Main Authors: Klara Livia Valko, Tong Zhang
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2021-01-01
Series:ADMET and DMPK
Online Access:https://www.pub.iapchem.org/ojs/index.php/admet/article/view/929