Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter

Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter

Abstract Background Gliomas are the most common primary tumors in central nervous system. The prognosis of the patients with glioma is poor regardless of the development of therapeutic strategies. Its aggressive behavior mainly depends on the potent ability of proliferation. The transcription factor...

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Bibliographic Details
Main Authors: Dian-gang Chen, Bo Zhu, Sheng-qing Lv, Hongfan Zhu, Jinliang Tang, Changlin Huang, Qingrui Li, Pu Zhou, Dong-lin Wang, Guang-hui Li
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
EGR1
CCND1
Glioma
Proliferation
Online Access:http://link.springer.com/article/10.1186/s13046-017-0656-4

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http://link.springer.com/article/10.1186/s13046-017-0656-4

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