Methionine synthase A2756G and reduced folate carrier1 A80G gene polymorphisms as maternal risk factors for Down syndrome in Egypt

Methionine synthase A2756G and reduced folate carrier1 A80G gene polymorphisms as maternal risk factors for Down syndrome in Egypt

Background: Polymorphisms of genes encoding enzymes involved in folate metabolism have long been hypothesized to be maternal risk factors for Down syndrome, however, results are conflicting and inconclusive. Aim of the study: To analyze the effect of methionine synthase (MTR) A2756G, and reduced fol...

Full description

Bibliographic Details
Main Authors: Maha Moustafa, Elham Gaber, Gamal Abo El Fath
Format: Article
Language:English
Published: SpringerOpen 2016-04-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Down syndrome
Methionine synthase
Reduced folate carrier
Gene polymorphism
Maternal risk
Egypt
Online Access:http://www.sciencedirect.com/science/article/pii/S1110863015001135

Internet

http://www.sciencedirect.com/science/article/pii/S1110863015001135

Similar Items