Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment.

Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment.

Antimicrobial peptides (AMPs) protect the host intestinal mucosa against microorganisms. Abnormal expression of defensins was shown in inflammatory bowel disease (IBD), but it is not clear whether this is a primary defect. We investigated the impact of anti-inflammatory therapy with infliximab on th...

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Bibliographic Details
Main Authors: Ingrid Arijs, Gert De Hertogh, Katleen Lemaire, Roel Quintens, Leentje Van Lommel, Kristel Van Steen, Peter Leemans, Isabelle Cleynen, Gert Van Assche, Séverine Vermeire, Karel Geboes, Frans Schuit, Paul Rutgeerts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2776509?pdf=render

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http://europepmc.org/articles/PMC2776509?pdf=render

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