Global and gene-specific DNA methylation in adult type 2 diabetic individuals: a protocol for a systematic review

Abstract Background DNA methylation (global and gene-specific) has been reported as an epigenetic mechanism that could be involved in the pathogenesis of type 2 diabetes mellitus (T2DM). Furthermore, epigenetic therapy has been suggested as a future possibility for T2DM treatment. Epigenetic changes...

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Bibliographic Details
Main Authors: Tinashe Mutize, Zibusiso Mkandla, Bongani B. Nkambule
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Systematic Reviews
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13643-018-0708-7