Temporal and spatial heterogeneity of programmed cell death 1-Ligand 1 expression in malignant mesothelioma

Background: Programmed Cell Death 1-Ligand 1 (PD-L1) and Programmed Death Protein 1 (PD-1) blocking antibodies are promising immunotherapies for malignancies. We have previously shown PD-L1 expression in 40% of malignant mesothelioma (MM); however, the temporal and spatial heterogeneity of its expre...

Full description

Bibliographic Details
Main Authors: Simone B. S. P. Terra, Aaron S. Mansfield, Haidong Dong, Tobias Peikert, Anja C. Roden
Format: Article
Language:English
Published: Taylor & Francis Group 2017-11-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1356146