Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes

Genetic variations at the Apolipoprotein E (ApoE) and microtubule-associated protein tau (MAPT) loci have been implicated in multiple neurogenerative diseases, but their exact molecular mechanisms are unclear. In this study, we performed transcript level linear modelling using the blood whole transc...

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Bibliographic Details
Main Authors: Sulev Koks, Abigail L. Pfaff, Vivien J. Bubb, John P. Quinn
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/3/423