Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival

Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival

Objectives: Few reports have explored clinical biomarkers, including those identified by targeted exome sequencing (TES) of surgically resected small-cell lung cancer (SCLC) and correlation with patient survival. Patients and methods: We collected formalin-fixed paraffin-embedded tumor samples from...

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Bibliographic Details
Main Authors: Hiroshi Yokouchi, Hiroshi Nishihara, Toshiyuki Harada, Shigeo Yamazaki, Hajime Kikuchi, Satoshi Oizumi, Hidetaka Uramoto, Fumihiro Tanaka, Masao Harada, Kenji Akie, Fumiko Sugaya, Yuka Fujita, Kei Takamura, Tetsuya Kojima, Mitsunori Higuchi, Osamu Honjo, Yoshinori Minami, Naomi Watanabe, Masaharu Nishimura, Hiroyuki Suzuki, Hirotoshi Dosaka-Akita, Hiroshi Isobe
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Heliyon
Subjects:
Bioinformatics
Genetics
Cancer research
Respiratory system
Clinical genetics
Surgery
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020312834

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http://www.sciencedirect.com/science/article/pii/S2405844020312834

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