Parallel immunizations of rabbits using the same antigen yield antibodies with similar, but not identical, epitopes.

A problem for the generation of polyclonal antibodies is the potential difficulties for obtaining a renewable resource due to batch-to-batch variations when the same antigen is immunized into several separate animals. Here, we have investigated this issue by determining the epitopes of antibodies ge...

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Bibliographic Details
Main Authors: Barbara Hjelm, Björn Forsström, John Löfblom, Johan Rockberg, Mathias Uhlén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284606/?tool=EBI