The protective mechanism of SIRT1 on cartilage through regulation of LEF-1
Abstract Background Osteoarthritis (OA) is a chronic degenerative disease that suppresses middle-aged and older people worldwide. Silent information regulator 1(SIRT-1) is associated with several age-related diseases, such as cardiovascular diseases, neurodegenerative diseases and tumors, etc. The p...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | BMC Musculoskeletal Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12891-021-04516-x |