A comparison of methods for studying the tumor microenvironment's spatial heterogeneity in digital pathology specimens

A comparison of methods for studying the tumor microenvironment's spatial heterogeneity in digital pathology specimens

Background: The tumor microenvironment is highly heterogeneous, and it is understood to affect tumor progression and patient outcome. A number of studies have reported the prognostic significance of tumor-infiltrating lymphocytes and tumor budding in colorectal cancer (CRC). However, the significanc...

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Bibliographic Details
Main Authors: Ines Panicou Nearchou, Daniel Alexander Soutar, Hideki Ueno, David James Harrison, Ognjen Arandjelovic, Peter David Caie
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Pathology Informatics
Subjects:
getis-ord analysis
heatmap analysis
lymphocytic infiltration
spatial heterogeneity
tumor prognosis
Online Access:http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2021;volume=12;issue=1;spage=6;epage=6;aulast=Nearchou

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http://www.jpathinformatics.org/article.asp?issn=2153-3539;year=2021;volume=12;issue=1;spage=6;epage=6;aulast=Nearchou

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