MLH1 and MSH2 mismatch repair protein profile using immunohistochemistry in Nepalese colorectal cancer patients

MLH1 and MSH2 mismatch repair protein profile using immunohistochemistry in Nepalese colorectal cancer patients

BACKGROUND Hereditary nonpolyposis colorectal cancer, or Lynch syndrome, caused by germline mutations or genetic defects in mismatch repair (MMR) genes (MLH1, MSH2, PMS2, MSH6, and epithelial cellular adhesion molecule), is an autosomal dominant condition accounting for 2–5% of all colorectal carci...

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Bibliographic Details
Main Authors: Matrika Bhattarai, Wan Khairunnisa Wan Juhari, Raju Lama, Chin Bahadur Pun, Wardah Yusof, Wan Faiziah Wan Abdul Rahman, Andee Dzulkarnaen Zakaria, Khairul Bariah Ahmad Amin Noordin, Tilak R. Shrestha, Bin Alwi Zilfalil
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2020-07-01
Series:Medical Journal of Indonesia
Subjects:
colorectal cancer
immunohistochemistry
mismatch repair
MutL homolog 1
MutS homolog 2
Online Access:https://mji.ui.ac.id/journal/index.php/mji/article/view/3633

Internet

https://mji.ui.ac.id/journal/index.php/mji/article/view/3633

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