The Protective Role of the Carbohydrate Response Element Binding Protein in the Liver: The Metabolite Perspective

The Carbohydrate response element binding protein, ChREBP encoded by the MLXIPL gene, is a transcription factor that is expressed at high levels in the liver and has a prominent function during consumption of high-carbohydrate diets. ChREBP is activated by raised cellular levels of phosphate ester i...

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Bibliographic Details
Main Authors: Loranne Agius, Shruti S. Chachra, Brian E. Ford
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Endocrinology
Subjects:
ATP
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.594041/full