Genetic and epigenetic modifications of F1 offspring’s sperm cells following in utero and lactational combined exposure to nicotine and ethanol

Abstract It is well established that maternal lifestyle during pregnancy and lactation affects the intrauterine programming of F1 offspring. However, despite the co-use of alcohol and nicotine is a common habit, the effects of exposure to both substances on the reproductive system of F1 male offspri...

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Bibliographic Details
Main Authors: Athareh Pabarja, Sepideh Ganjalikhan Hakemi, Elahe Musanejad, Massood Ezzatabadipour, Seyed Noureddin Nematollahi-Mahani, Ali Afgar, Mohammad Reza Afarinesh, Tahereh Haghpanah
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91739-6