Immunogenicity and efficacy of flagellin-fused vaccine candidates targeting 2009 pandemic H1N1 influenza in mice.

Immunogenicity and efficacy of flagellin-fused vaccine candidates targeting 2009 pandemic H1N1 influenza in mice.

We have previously demonstrated that the globular head of the hemagglutinin (HA) antigen fused to flagellin of Salmonella typhimurium fljB (STF2, a TLR5 ligand) elicits protective immunity to H1N1 and H5N1 lethal influenza infections in mice (Song et al., 2008, PLoS ONE 3, e2257; Song et al., 2009,...

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Bibliographic Details
Main Authors: Ge Liu, Bart Tarbet, Langzhou Song, Lucia Reiserova, Bruce Weaver, Yan Chen, Hong Li, Fu Hou, Xiangyu Liu, Jason Parent, Scott Umlauf, Alan Shaw, Lynda Tussey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3110246?pdf=render

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http://europepmc.org/articles/PMC3110246?pdf=render

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