Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis

<p>Abstract</p> <p>Background</p> <p>Although integrins have been implicated in the progression of breast cancer, the exact mechanism whereby they exert this regulation is clearly not understood. To understand the role of integrins in breast cancer, we examined the expr...

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Bibliographic Details
Main Authors: Hazari Siddhartha, Bao Lili, Jain Prachi, Rathinam Rajamani, Baranwal Somesh, Shenouda Sylvia, Wang Yanfang, Dash Srikanta, Alahari Suresh K
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/84